A group of scientists examined the “proximal origin of SARS-CoV-2” and looked at the genome to see how it could have arisen. This inevitably dealt with a lot of conspiracy theories regarding the origin of the virus. The article is very technical, so someone took to Reddit to explain the key points:
It is improbable that SARS-CoV-2 emerged through laboratory manipulation of a related SARS-CoV-like coronavirus. As noted above, the RBD of SARS-CoV-2 is optimized for binding to human ACE2 with an efficient solution different from those previously predicted.
They’re saying here that if this was an engineered virus, the binding domain (the region of the virus that initially binds to a human cell and allows it to infect that cell) would be more optimized. COVID-19’s binding domain only sorta-okay binds.